| Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure |
Li, XS; Zhou, LN; Gao, BQ; Li, GY; Wang, X; Wang, Y; Wei, J; Han, WY; Wang, ZX; Li, JF; Gao, RZ; Zhu, JJ; Xu, WC; Wu, J; Yang, B; Sun, XD; Yang, L; Chen, J |
Article |
NATURE COMMUNICATIONS |
2022 |
| High-protein diet prevents fat mass increase after dieting by counteracting Lactobacillus-enhanced lipid absorption |
Wuling Zhong, Hui Wang, Yale Yang, Yali Zhang, Hejin Lai, Yalan Cheng, Huimin Yu, Ning Feng, Rui Huang, Shen Liu, Sheng Yang, Tongyang Hao, Baoyu Zhang, Hao Ying, Fang Zhang, Feifan Guo & Qiwei Zhai |
Article |
NATURE METABOLISM |
2022 |
| High-throughput mapping of single-neuron projection and molecular features by retrograde barcoded labeling |
Xu, PB; Peng, J; Yuan, TL; Chen, ZQ; He, H; Wu, ZY; Li, T; Li, XD; Wang, LY; Gao, L; Yan, J; Wei, W; Li, CT; Luo, ZG; Chen, YJ; Day, JJ |
|
ELIFE |
2024 |
| High-throughput prediction of enzyme promiscuity based on substrate-product pairs |
Xing, HD; Cai, PL; Liu, DL; Han, MY; Liu, J; Le, YY; Zhang, DC; Hu, QN |
|
BRIEFINGS IN BIOINFORMATICS |
2024 |
| Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade |
Zhang, Q; Meng, FS; Chen, SS; Plouffe, SW; Wu, SY; Liu, SD; Li, XR; Zhou, RY; Wang, JX; Zhao, B; Liu, JM; Qin, J; Zou, J; Feng, XH; Guan, KL; Xu, PL |
Article |
NATURE CELL BIOLOGY |
2017 |
| Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2 |
Liu, QL; Pang, J; Wang, LA; Huang, ZW; Xu, J; Yang, XX; Xie, QB; Huang, YQ; Tang, T; Tong, DL; Liu, GL; Wang, LF; Zhang, DZ; Ma, Q; Xiao, HL; Lan, WH; Qin, J; Jiang, J |
Article |
JOURNAL OF PATHOLOGY |
2021 |
| Histone demethylase PHF8 promotes prostate cancer metastasis via the E2F1-SNAI1 axis |
Wang, Z; Tang, P; Xiao, HY; Peng, S; Chen, J; Wang, YP; Xu, J; Yan, Q; Zhang, JY; Deng, J; Ma, Q; Zhu, HL; Luo, WM; Zhang, DZ; Wang, LF; Qin, J; Lan, WH; Jiang, J; Liu, QL |
|
JOURNAL OF PATHOLOGY |
2024 |
| Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis |
Yuan, HR; Li, N; Fu, D; Ren, J; Hui, JY; Peng, JJ; Liu, YF; Qiu, T; Jiang, M; Pan, Q; Han, Y; Wang, XM; Li, QT; Qin, J |
Article |
JOURNAL OF CLINICAL INVESTIGATION |
2017 |
| Histone methyltransferase WHSC1 loss dampens MHC-I antigen presentation pathway to impair IFN-gamma stimulated antitumor immunity |
Ren, JL; Li, N; Pei, SY; Lian, YN; Li, L; Peng, YC; Liu, QL; Guo, JC; Wang, XG; Han, Y; Zhang, GY; Wang, HL; Li, YQ; Jiang, J; Li, QT; Tan, MJ; Peng, JJ; Hu, GH; Xiao, YC; Li, X; Lin, MB; Qin, J |
Article |
JOURNAL OF CLINICAL INVESTIGATION |
2022 |
| Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting |
Zhao, YX; Li, S; Chen, YH; Wang, YC; Wei, YD; Zhou, TT; Zhang, YW; Yang, YY; Chen, LL; Liu, Y; Hu, C; Zhou, B; Ding, QR |
Article |
MOLECULAR CELL |
2023 |
| HIV infection alters the human epigenetic landscape |
Chen, L; Zhang, SQ; Pan, XY; Hu, XH; Zhang, YH; Yuan, F; Huang, T; Cai, YD |
Article |
GENE THERAPY |
2019 |
| HnRNPA2B1 promotes the proliferation of breast cancer MCF-7 cells via the STAT3 pathway |
Gao, LB; Zhu, XL; Shi, JX; Yang, L; Xu, ZQ; Shi, SL |
Article |
JOURNAL OF CELLULAR BIOCHEMISTRY |
2021 |
| Host-Microbiome Synergistic Control on Sphingolipid Metabolism by Mechanotransduction in Model Arthritis |
Zhou, XY; Devescovi, V; Liu, YH; Dent, JE; Nardini, C |
Article |
BIOMOLECULES |
2019 |
| hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating beta-Catenin Signaling |
Cai, Z; Qian, ZY; Jiang, H; Ma, N; Li, Z; Liu, LY; Ren, XX; Shang, YR; Wang, JJ; Li, JJ; Liu, DP; Zhang, XP; Feng, D; Ni, QZ; Feng, YY; Li, N; Zhou, XY; Wang, X; Bao, Y; Zhang, XL; Deng, YZ; Xie, D |
Article |
CANCER RESEARCH |
2018 |
| hReg-CNCC reconstructs a regulatory network in human cranial neural crest cells and annotates variants in a developmental context |
Feng, ZY; Duren, ZN; Xiong, ZY; Wang, SJ; Liu, F; Wong, WH; Wang, Y |
Article |
COMMUNICATIONS BIOLOGY |
2021 |
| Hsa_circ_0006692 Promotes Lung Cancer Progression via miR-205-5p/CDK19 Axis |
Liao, JR; Chen, Z; Luo, XG; Su, Y; Huang, T; Xu, HP; Lin, KY; Zheng, QL; Zhang, LR; Lin, G; Lin, XD |
Article |
GENES |
2022 |
| Hsp90 inhibition destabilizes Ezh2 protein in alloreactive T cells and reduces graft-versus-host disease in mice |
Huang, QR; He, S; Tian, YY; Gu, YT; Chen, P; Li, CH; Huang, JF; Liu, YN; Yu, HS; Jin, M; Hu, SY; Tong, Q; Ma, AQ; Jin, J; Hexner, E; Fung, H; Reshef, R; Zhang, Y; Zhang, YY |
Article |
BLOOD |
2017 |
| HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation |
Wang, ZS; Yan, CH; Du, QZ; Huang, YY; Li, XZ; Zeng, D; Mao, RZ; Gurram, RK; Cheng, SP; Gu, WP; Zhu, L; Fan, WG; Ma, LY; Ling, ZY; Qiu, J; Li, DS; Liu, EM; Zhang, YG; Fang, YR; Zhu, JF; Sun, B |
Article |
CELLULAR & MOLECULAR IMMUNOLOGY |
2023 |
| Human cleaving embryos enable robust homozygotic nucleotide substitutions by base editors |
Zhang, ML; Zhou, CY; Wei, Y; Xu, CL; Pan, H; Ying, WQ; Sung, YD; Sun, Y; Xiao, QQ; Yao, N; Zhong, WX; Li, Y; Wu, KL; Yuan, G; Mitalipov, S; Chen, ZJ; Yang, H |
Article |
GENOME BIOLOGY |
2019 |
| Human embryonic stem cell-derived cardiovascular progenitor cells stimulate cardiomyocyte cell cycle activity via activating the PI3K/ Akt pathway |
Chen, ZY; Yu, XJ; Ke, MX; Li, H; Jiang, Y; Zhang, P; Tan, JL; Cao, N; Yang, HT |
|
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY |
2024 |
| Human Embryonic Stem Cell-Derived Cardiovascular Progenitors Repair Infarcted Hearts Through Modulation of Macrophages via Activation of Signal Transducer and Activator of Transcription 6 |
Wang, JX; Liu, ML; Wu, Q; Li, Q; Gao, L; Jiang, Y; Deng, BX; Huang, W; Bi, W; Chen, ZY; Chin, YE; Paul, C; Wang, YG; Yang, HT |
Article |
ANTIOXIDANTS & REDOX SIGNALING |
2019 |
| Human Genomic Signatures of Brain Oscillations During Memory Encoding |
Berto, S; Wang, GZ; Germi, J; Lega, BC; Konopka, G |
Article |
CEREBRAL CORTEX |
2018 |
| Human-specific features of spatial gene expression and regulation in eight brain regions |
Xu, C; Li, Q; Efimova, O; He, L; Tatsumoto, S; Stepanova, V; Oishi, T; Udono, T; Yamaguchi, K; Shigenobu, S; Kakita, A; Nawa, H; Khaitovich, P; Go, Y |
Article |
GENOME RESEARCH |
2018 |
| Human-unique brain cell clusters are associated with learning disorders and human episodic memory activity |
Ma, JJ; Qi, RC; Wang, J; Berto, S; Wang, GZ |
|
MOLECULAR PSYCHIATRY |
2024 |
| Hyperbaric oxygen therapy for healthy aging: From mechanisms to therapeutics |
Fu, QY; Duan, R; Sun, Y; Li, QF |
Article |
REDOX BIOLOGY |
2022 |
| HyperChIP: identification of hypervariable signals across ChIP-seq or ATAC-seq samples |
Chen, HJ; Tu, SQ; Yuan, CZ; Tian, F; Zhang, YJ; Sun, YH; Shao, Z |
Article |
GENOME BIOLOGY |
2022 |
| Hyperoside Ameliorates DSS-Induced Colitis through MKRN1-Mediated Regulation of PPAR gamma Signaling and Th17/Treg Balance |
Cheng, C; Zhang, W; Zhang, C; Ji, P; Wu, XH; Sha, Z; Chen, X; Wang, YK; Chen, YG; Cheng, HB; Shi, LY |
Article; Early Access |
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY |
|
| Hypomethylation of CNTFR alpha is associated with proliferation and poor prognosis in lower grade gliomas |
Fan, K; Wang, XW; Zhang, JW; Ramos, RI; Zhang, HB; Li, CJ; Ye, D; Kang, JS; Marzese, DM; Hoon, DSB; Hua, W |
Article |
SCIENTIFIC REPORTS |
2017 |
| Hypothesis: hematogenous metastatic cancer cells of solid tumors may disguise themselves as memory macrophages for metastasis |
Jiang, C; Wu, JX |
|
FRONTIERS IN ONCOLOGY |
2024 |
| Hypoxic Exosomal circPLEKHM1-Mediated Crosstalk between Tumor Cells and Macrophages Drives Lung Cancer Metastasis |
Wang, DL; Wang, S; Jin, MM; Zuo, Y; Wang, JP; Niu, Y; Zhou, Q; Chen, JW; Tang, XR; Tang, WX; Liu, XY; Yu, H; Yan, WJ; Wei, HH; Huang, G; Song, SL; Tang, S |
|
ADVANCED SCIENCE |
2024 |
| IDeAS: an interactive database for dysregulated alternative splicing in cancers across Chinese and western patients |
Zhou, HW; Yuan, LY; Ju, YH; Hu, Y; Wang, SQ; Cao, RF; Wang, ZF; Zhang, GQ |
|
JOURNAL OF MOLECULAR CELL BIOLOGY |
2024 |
| Identification and Analysis of Blood Gene Expression Signature for Osteoarthritis With Advanced Feature Selection Methods |
Li, J; Lan, CN; Kong, Y; Feng, SS; Huang, T |
Article |
FRONTIERS IN GENETICS |
2018 |
| Identification and analysis of the cleavage site in a signal peptide using SMOTE, dagging, and feature selection methods |
Wang, SP; Wang, DL; Li, JR; Huang, T; Cai, YD |
Article |
MOLECULAR OMICS |
2018 |
| Identification and Application of Gene Expression Signatures Associated with Lifespan Extension |
Tyshkovskiy, A; Bozaykut, P; Borodinova, AA; Gerashchenko, MV; Ables, GP; Garratt, M; Khaitovich, P; Clish, CB; Miller, RA; Gladyshev, VN |
Article |
CELL METABOLISM |
2019 |
| Identification and characterization of functional modules reflecting transcriptome transition during human neuron maturation |
He, ZS; Yu, QH |
Article |
BMC GENOMICS |
2018 |
| Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B |
Wang, Z; Li, ZX; Zhao, WC; Huang, HB; Wang, JQ; Zhang, H; Lu, JY; Wang, RN; Li, W; Cheng, Z; Xu, WL; Zhu, D; Zhou, LS; Jiang, W; Yu, L; Liu, JY; Luo, C; Zhu, H; Ye, D; Pan, WJ; Ju, JH; Dang, YJ |
Article |
ACTA PHARMACOLOGICA SINICA |
2021 |
| Identification and functional implication of variants associated with skin pigmentation in Chinese population |
Cai, X; Liu, X; Zhao, Y; Xu, K; Li, W; Yang, Z; Wang, S |
Meeting Abstract |
JOURNAL OF INVESTIGATIVE DERMATOLOGY |
2022 |
| Identification and quantification of small exon-containing isoforms in long-read RNA sequencing data |
Liu, Z; Zhu, CC; Steinmetz, LM; Wei, W |
Article; Early Access |
NUCLEIC ACIDS RESEARCH |
2023 |
| Identification and validation of microbial biomarkers from cross-cohort datasets using xMarkerFinder |
Gao, WX; Lin, WL; Li, Q; Chen, WN; Yin, WJ; Zhu, XY; Gao, S; Liu, L; Li, WJ; Wu, DF; Zhang, GQ; Zhu, RX; Jiao, N |
|
NATURE PROTOCOLS |
2024 |
| Identification of a cytokine-cytokine receptor interaction gene signature for predicting clinical outcomes in patients with colorectal cancer |
Dong, CP; Wang, X; Xu, HL; Zhan, XH; Ren, H; Liu, ZH; Liu, G; Liu, L |
Article |
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE |
2017 |
| Identification of a novel series of anti-inflammatory and anti-oxidative phospholipid oxidation products containing the cyclopentenone moiety in vitro and in vivo: Implication in atherosclerosis |
Lu, JH; Guo, SY; Xue, XL; Chen, Q; Ge, J; Zhuo, YJ; Zhong, HQ; Chen, BX; Zhao, MM; Han, W; Suzuki, T; Zhu, MJ; Xia, L; Schneider, C; Blackwell, TS; Porter, NA; Zheng, LM; Tsimikas, S; Yin, HY |
Article |
JOURNAL OF BIOLOGICAL CHEMISTRY |
2017 |
| Identification of a rhodanine derivative BML-260 as a potent stimulator of UCP1 expression |
Feng, ZH; Wei, YD; Zhang, YX; Qiu, Y; Liu, XJ; Su, L; Liang, NN; Yin, HY; Ding, QR |
Article |
THERANOSTICS |
2019 |
| Identification of a small molecule SR9009 that activates NRF2 to counteract cellular senescence |
Gao, LB; Wang, YH; Liu, ZH; Sun, Y; Cai, P; Jing, Q |
Article |
AGING CELL |
2021 |
| Identification of BAF60b as a Chromatin-Remodeling Checkpoint of Diet-Induced Fatty Liver Disease |
Zhong, J; Ji, XY; Zhao, YL; Jia, YH; Song, CR; Lv, JH; Chen, YY; Zhou, YP; Lv, X; Yang, ZY; Zhang, ZY; Xu, QY; Wang, WH; Chen, HY; Cui, AY; Li, Y; Meng, ZX |
|
DIABETES |
2024 |
| Identification of Candidate Genes Associated with Trichothecene Biosynthesis in Fusarium graminearum Species Complex Combined with Transcriptomic and Proteomic Analysis |
Wang, JH; Lin, SH; Zhu, GH; Zhao, ZY; Wang, HY; Zhou, MP; Zhao, XM; Wu, AB |
Article |
MICROORGANISMS |
2022 |
| Identification of Candidate Genes Related to Inflammatory Bowel Disease Using Minimum Redundancy Maximum Relevance, Incremental Feature Selection, and the Shortest-Path Approach |
Yuan, F; Zhang, YH; Kong, XY; Cai, YD |
Article |
BIOMED RESEARCH INTERNATIONAL |
2017 |
| Identification of Cell Cycle-Regulated Genes by Convolutional Neural Network |
Liu, CL; Cui, P; Huang, T |
Article |
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING |
2017 |
| Identification of Cell Markers and Their Expression Patterns in Skin Based on Single-Cell RNA-Sequencing Profiles |
Zhou, XC; Ding, SJ; Wang, DL; Chen, L; Feng, KY; Huang, T; Li, ZD; Cai, YD |
Article |
LIFE-BASEL |
2022 |
| Identification of Chronic Hypersensitivity Pneumonitis Biomarkers with Machine Learning and Differential Co-expression Analysis |
Zhang, HW; Wang, S; Huang, T |
Article |
CURRENT GENE THERAPY |
2021 |
| Identification of Colon Immune Cell Marker Genes Using Machine Learning Methods |
Yang, Y; Zhang, YH; Ren, JX; Feng, KY; Li, ZD; Huang, T; Cai, YD |
Article |
LIFE-BASEL |
2023 |
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