| Integrative Functional Genomics Identifies Systemic Lupus Erythematosus Causal Genetic Variant in the IRF5 Risk Locus |
Hou, GJ; Zhou, T; Xu, N; Yin, ZH; Zhu, XY; Zhang, YT; Cui, YE; Ma, JY; Tang, YJ; Cheng, ZR; Shen, YW; Chen, YS; Zou, LH; Wang, YF; Yin, ZH; Guo, Y; Ding, HH; Ye, ZZ; Shen, N |
Article |
ARTHRITIS & RHEUMATOLOGY |
2023 |
| Integrative proteogenomic profiling of high-risk prostate cancer samples from Chinese patients indicates metabolic vulnerabilities and diagnostic biomarkers |
Dong, BJ; Xu, JY; Huang, YQ; Guo, JC; Dong, Q; Wang, YQ; Li, N; Liu, QL; Zhang, MY; Pan, Q; Wang, HL; Jiang, J; Chen, BR; Shen, DQ; Ma, YM; Zhai, LH; Zhang, J; Li, J; Xue, W; Tan, MJ; Qin, J |
|
NATURE CANCER |
2024 |
| Integrative Proteome and Ubiquitinome Analyses Reveal the Substrates of BTBD9 and Its Underlying Mechanism in Sleep Regulation |
Gao, ZF; Wang, AZ; Zhao, YX; Zhang, XX; Yuan, XS; Li, NN; Xu, C; Wang, SM; Zhu, YX; Zhu, JY; Guan, J; Liu, F; Yin, SK |
Article |
ACS OMEGA |
2022 |
| Integrin alpha E beta 7(+) T cells direct intestinal stem cell fate decisions via adhesion signaling |
Chen, SY; Zheng, YJ; Ran, XJ; Du, H; Feng, H; Yang, L; Wen, YT; Lin, CD; Wang, SH; Huang, MW; Yan, ZJ; Wu, DQ; Wang, HY; Ge, GX; Zeng, A; Zeng, YA; Chen, JF |
Article; Early Access |
CELL RESEARCH |
|
| Interaction of n-3 polyunsaturated fatty acids with host CD36 genetic variant for gut microbiome and blood lipids in human cohorts |
Miao, ZL; Chen, GD; Huo, SF; Fu, YQ; Wu, MY; Xu, FZ; Jiang, ZL; Tang, J; Gou, WL; Xiao, CM; Liu, YP; Wu, YY; Sun, TY; Sun, L; Shen, LR; Lin, X; Chen, YM; Zheng, JS |
Article |
CLINICAL NUTRITION |
2022 |
| Interactions among maternal smoking, breastfeeding, and offspring genetic factors on the risk of adult-onset hypertension |
Liang, JJ; Fu, ZQ; Liu, Q; Shen, YH; Zhang, X; Weng, ZK; Xu, J; Li, WX; Xu, C; Zhou, Y; Gu, AH |
Article |
BMC MEDICINE |
2022 |
| Interactions of human embryonic stem cell-derived cardiovascular progenitor cells with immobilized extracellular matrix proteins |
Lu, JZ; Kaestle, K; Huang, JJ; Liu, Q; Zhang, P; Gao, L; Gardiner, J; Thissen, H; Yang, HT |
Article |
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A |
2017 |
| Interleukin-17A-promoted MSC2 polarization related with new bone formation of ankylosing spondylitis |
He, T; Huan, Y; Zhang, C; Liu, DH; Cheng, C; Xu, WD; Zhang, XL |
Article |
ONCOTARGET |
2017 |
| Intermittent administration of a fasting-mimicking diet intervenes in diabetes progression, restores beta cells and reconstructs gut microbiota in mice |
Wei, SY; Han, RM; Zhao, JY; Wang, S; Huang, MQ; Wang, YN; Chen, Y |
Article |
NUTRITION & METABOLISM |
2018 |
| Intermittent administration of a fasting-mimicking diet reduces intestinal inflammation and promotes repair to ameliorate inflammatory bowel disease in mice |
Song, S; Bai, MJ; Ling, ZQ; Lin, YJ; Wang, S; Chen, Y |
Article |
JOURNAL OF NUTRITIONAL BIOCHEMISTRY |
2021 |
| Intermittent Caloric Restriction Promotes Erythroid Development and Ameliorates Phenylhydrazine-Induced Anemia in Mice |
Bai, MJ; Cao, PJ; Lin, YJ; Yu, PC; Song, S; Chen, LL; Wang, L; Chen, Y |
Article |
FRONTIERS IN NUTRITION |
2022 |
| Intermittent caloric restriction with a modified fasting-mimicking diet ameliorates autoimmunity and promotes recovery in a mouse model of multiple sclerosis |
Bai, MJ; Wang, Y; Han, RM; Xu, LJ; Huang, MQ; Zhao, JY; Lin, YJ; Song, S; Chen, Y |
Article |
JOURNAL OF NUTRITIONAL BIOCHEMISTRY |
2021 |
| Intermittent Leucine Deprivation Produces Long-lasting Improvement in Insulin Sensitivity by Increasing Hepatic Gcn2 Expression |
Yin, HR; Yuan, FX; Jiao, FX; Niu, YG; Jiang, XX; Deng, JL; Guo, YJ; Chen, SH; Zhai, QW; Hu, C; Li, YM; Guo, FF |
Article |
DIABETES |
2022 |
| Intermittent protein restriction improves glucose homeostasis in Zucker diabetic fatty rats and single-cell sequencing reveals distinct changes in ,B cells |
Li, CC; Zhu, J; Wei, SY; Ye, XY; Yang, LZX; Wang, ZA; Chen, Y |
Article |
JOURNAL OF NUTRITIONAL BIOCHEMISTRY |
2023 |
| Intermittent protein restriction protects islet 13 cells and improves glucose homeostasis in diabetic mice |
Wei, SY; Li, CC; Luo, XM; Yang, LZX; Yu, L; Wang, QT; Meng, ZX; Wang, T; Chen, Y |
Article |
SCIENCE BULLETIN |
2022 |
| International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System |
Lechner, M; Takahashi, Y; Turri-Zanoni, M; Ferrari, M; Liu, J; Counsell, N; Mattavelli, D; Rampinelli, V; Vermi, W; Lombardi, D; Saade, R; Park, KW; Schartinger, VH; Franchi, A; Facco, C; Sessa, F; Battocchio, S; Fenton, TR; Vaz, FM; O'Flynn, P; Howard, D; Stimpson, P; Wang, S; Hannan, SA; Unadkat, S; Hughes, J; Dwivedi, R; Forde, CT; Randhawa, P; Gane, S; Joseph, J; Andrews, PJ; Dave, M; Fleming, JC; Thomson, D; Zhu, TY; Teschendorff, A; Royle, G; Steele, C; Jimenez, JE; Laco, J; Wang, EW; Snyderman, C; Lacy, PD; Woods, R; O'Neill, JP; Saraswathula, A; Kaur, RP; Zhao, TN; Ramanathan, M; Gallia, GL; London, NR; Le, QT; West, RB; Patel, ZM; Nayak, JV; Hwang, PH; Hermsen, M; Llorente, J; Facchetti, F; Nicolai, P; Bossi, P; Castelnuovo, P; Jay, A; Carnell, D; Forster, MD; Bell, DM; Lund, VJ; Hanna, EY |
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JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE |
2023 |
| Interpreting Functional Impact of Genetic Variations by Network QTL for Genotype-Phenotype Association Study |
Yuan, K; Zeng, T; Chen, LA |
Article |
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY |
2022 |
| Inter-tissue convergence of gene expression during ageing suggests age-related loss of tissue and cellular identity |
Izgi, H; Han, DD; Isildak, U; Huang, SY; Kocabiyik, E; Khaitovich, P; Somel, M; Donertas, HM |
Article |
ELIFE |
2022 |
| Intestinal activating transcription factor 4 regulates stress-related behavioral alterations via paraventricular thalamus in male mice |
Yuan, FX; Zhou, ZH; Wu, SM; Jiao, FX; Chen, L; Fang, LL; Yin, HR; Hu, XM; Jiang, XX; Liu, K; Xiao, F; Jiang, HZ; Chen, SH; Liu, ZJ; Shu, YS; Guo, FF |
Article |
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA |
2023 |
| Intestinal Epithelial Cell-specific Deletion of Cytokine-inducible SH2-containing Protein Alleviates Experimental Colitis in Ageing Mice |
Hu, XM; Jiao, FX; Deng, JL; Zhou, ZH; Chen, SH; Liu, CQ; Liu, ZJ; Guo, FF |
Article; Early Access |
JOURNAL OF CROHNS & COLITIS |
2023 |
| Intestinal monocarboxylate transporter 1 mediates lactate transport in the gut and regulates metabolic homeostasis of mouse in a sex-dimorphic pattern |
Shuo Wang, Lingling Zhang, Jingyu Zhao, Meijuan Bai, Yijun Lin, Qianqian Chu, Jue Gong, Ju Qiu, Yan Chen |
Article |
Life Metabolism |
2023 |
| Intracellular osteopontin potentiates the immunosuppressive activity of mesenchymal stromal cells |
Yang, WL; Jin, M; Gu, YT; Zhao, XA; Zhu, LQ; He, S; Wang, H; Ding, XY; Wang, B; Jiang, TW; Xiao, YC; Zhou, GQ; Huang, JF; Zhang, YY |
|
STEM CELL RESEARCH & THERAPY |
2024 |
| Intraplatelet miRNA-126 regulates thrombosis and its reduction contributes to platelet inhibition |
Zhang, LJ; Hu, YX; Huang, RZ; Xu, YY; Dong, SH; Guo, FH; Guo, JJ; Qiu, JJ; Cao, ZY; Wei, LJ; Mao, JH; Lyu, A; Liu, JL; Zhao, XX; Guo, ZF; Jing, Q |
|
CARDIOVASCULAR RESEARCH |
2024 |
| Intrinsic RIG-I restrains STAT5 activation to modulate antitumor activity of CD8+T cells |
Jiang, XY; Lin, J; Shangguan, CF; Wang, XY; Xiang, B; Chen, J; Guo, HZ; Zhang, W; Zhang, J; Shi, Y; Zhu, J; Yang, H |
Article |
JOURNAL OF CLINICAL INVESTIGATION |
2023 |
| Introduction to the special issue on stem cells and their products for cardiac repair and regeneration |
Yang, HT; Zhou, B; Qian, L |
Editorial Material |
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY |
2023 |
| INTS6 promotes colorectal cancer progression by activating of AKT and ERK signaling |
Ding, XF; Chen, TW; Shi, Q; Nan, P; Wang, X; Xie, D; Li, JJ |
Article |
EXPERIMENTAL CELL RESEARCH |
2021 |
| Investigating gene methylation signatures for fetal intolerance prediction |
Zhang, YH; Li, ZD; Zeng, T; Chen, L; Li, H; Gamarra, M; Mansour, RF; Escorcia-Gutierrez, J; Huang, T; Cai, YD |
Article |
PLOS ONE |
2021 |
| In-vivo 3D imaging of Zebrafish's intersegmental vessel development by a bi-directional light-sheet illumination microscope |
Qin, XF; Chen, C; Wang, LB; Chen, XH; Liang, Y; Jin, X; Pan, WJ; Liu, ZY; Li, H; Yang, G |
Article |
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
2021 |
| In Vivo Exon Replacement in the Mouse Atp7b Gene by the Cas9 System |
Liu, LL; Cao, JC; Chang, QR; Xing, FY; Yan, GF; Fu, L; Wang, HY; Ma, ZW; Chen, XJ; Li, Y; Li, SG |
Article; Early Access |
HUMAN GENE THERAPY |
2019 |
| In vivo simultaneous transcriptional activation of multiple genes in the brain using CRISPR-dCas9-activator transgenic mice |
Zhou, HB; Liu, JL; Zhou, CY; Gao, N; Rao, ZP; Li, H; Hu, XD; Li, CL; Yao, X; Shen, XW; Sun, YD; Wei, Y; Liu, F; Ying, WQ; Zhang, JM; Tang, C; Zhang, X; Xu, HT; Shi, LY; Cheng, LP; Huang, PY; Yang, H |
Article |
NATURE NEUROSCIENCE |
2018 |
| Involvement of Transcriptional Factor Pbx1 in Peripheral B Cell Homeostasis to Constrain Lupus Autoimmunity |
Gu, SS; Zhang, JS; Han, XX; Ding, HH; Yao, C; Ye, ZZ; Yin, ZH; Hou, GJ; Jiang, Y; Qian, J; Zhou, HB; Guo, Q; Chen, S; Dai, D; Shen, N |
Article; Early Access |
ARTHRITIS & RHEUMATOLOGY |
2023 |
| Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation |
Yu, J; Shen, SY; Yan, Y; Liu, LX; Luo, RK; Liu, SN; Wu, YT; Li, YY; Jiang, JJ; Ying, H |
Article |
NUTRIENTS |
2023 |
| IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1(+) cells via the calcineurin-NFATc3-Etv2 pathway |
Wang, YJ; Huang, JJ; Liu, WQ; Kou, XC; Tang, HY; Wang, H; Yu, XJ; Gao, SR; Ouyang, KF; Yang, HT |
Article |
JOURNAL OF MOLECULAR CELL BIOLOGY |
2017 |
| IRES-mediated cap-independent translation, a path leading to hidden proteome |
Yang, Y; Wang, ZF |
Review |
JOURNAL OF MOLECULAR CELL BIOLOGY |
2019 |
| Irisin plays a pivotal role to protect the heart against ischemia and reperfusion injury |
Wang, H; Zhao, YT; Zhang, SY; Dubielecka, PM; Du, JF; Yano, NHR; Chin, YE; Zhuang, SG; Qin, GJ; Zhao, TC |
Article |
JOURNAL OF CELLULAR PHYSIOLOGY |
2017 |
| Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production |
Wang, ZZ; Yin, WJ; Zhu, LZ; Li, J; Yao, YK; Chen, FF; Sun, MM; Zhang, JY; Shen, N; Song, Y; Chang, X |
Article |
IMMUNITY |
2018 |
| Iron Status and Risk of Heart Disease, Stroke, and Diabetes: A Mendelian Randomization Study in European Adults |
Liu, YA; Clarke, R; Bennett, DA; Zong, G; Gan, W |
|
JOURNAL OF THE AMERICAN HEART ASSOCIATION |
2024 |
| Isolation and Characterization of Extracellular Vesicles Secreted from Human Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells. |
Wu, Qiang; Ke, Min-Xia; Yang, Huang-Tian |
|
Methods in molecular biology (Clifton, N.J.) |
2022 |
| ISX-9 potentiates CaMKII delta-mediated BMAL1 activation to enhance circadian amplitude |
Li, HL; Ou, JL; Li, YQ; Xu, NN; Li, Q; Wu, P; Peng, C; Tang, YC; Chang, HC |
Article |
COMMUNICATIONS BIOLOGY |
2022 |
| KANK4 Promotes Arteriogenesis by Potentiating VEGFR2 Signaling in a TALIN-1-Dependent Manner |
Zhang, CH; He, H; Dai, JN; Li, YX; He, J; Yang, W; Dai, JL; Han, F; Kong, WY; Wang, XH; Zheng, XJ; Zhou, J; Pan, WJ; Chen, ZW; Mahak, S; Zhang, YY; Guo, F; Hu, JH |
Article |
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY |
2022 |
| KCNQ1OT1 promotes genome-wide transposon repression by guiding RNA-DNA triplexes and HP1 binding |
Zhang, XL; Jiang, QL; Li, JY; Zhang, SQ; Cao, YQ; Xia, X; Cai, DH; Tan, JQ; Chen, JK; Han, JDJ |
Article |
NATURE CELL BIOLOGY |
2022 |
| Keratin 14-high subpopulation mediates lung cancer metastasis potentially through Gkn1 upregulation |
Yao, S; Huang, HY; Han, XK; Ye, Y; Qin, Z; Zhao, GX; Li, FM; Hu, GH; Hu, L; Ji, HB |
Article |
ONCOGENE |
2019 |
| Ketogenic diet-induced bile acids protect against obesity through reduced calorie absorption |
Li, X; Yang, J; Zhou, XF; Dai, C; Kong, MM; Xie, LS; Liu, CL; Liu, YL; Li, DD; Ma, XN; Dai, YX; Sun, Y; Jian, ZJ; Guo, XH; Lin, X; Li, YX; Sun, L; Liu, X; Jin, L; Tang, HR; Zheng, Y; Hong, SY |
|
NATURE METABOLISM |
2024 |
| Knockdown of IRE1 alpha inhibits colonic tumorigenesis through decreasing beta-catenin and IRE1 alpha targeting suppresses colon cancer cells |
Li, XX; Zhang, HS; Xu, YM; Zhang, RJ; Chen, Y; Fan, L; Qin, YQ; Liu, Y; Li, M; Fang, J |
Article |
ONCOGENE |
2017 |
| Knockdown of IRE1 alpha suppresses metastatic potential of colon cancer cells through inhibiting FN1-Src/FAK-GTPases signaling |
Xie, YH; Liu, C; Qin, YQ; Chen, JF; Fang, J |
Article |
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY |
2019 |
| Knockdown of NCOR2 Inhibits Cell Proliferation via BDNF/TrkB/ERK in NF1-Derived MPNSTs |
Li, YH; Chung, MH; Aimaier, R; Wei, CJ; Wang, W; Ge, LL; Zhu, BY; Guo, ZZ; Wang, MY; Gu, YH; Zhang, HB; Li, QF; Wang, ZC |
Article |
CANCERS |
2022 |
| Knocking out NEGATIVE REGULATOR OF PHOTOSYNTHESIS 1 increases rice leaf photosynthesis and biomass production in the field |
Chen, FM; Zheng, GY; Qu, MN; Wang, YJ; Lyu, MJA; Zhu, XG |
Article |
JOURNAL OF EXPERIMENTAL BOTANY |
2021 |
| Knockout of circRNAs by base editing back-splice sites of circularized exons |
Gao, X; Ma, XK; Li, X; Li, GW; Liu, CX; Zhang, J; Wang, Y; Wei, J; Chen, J; Chen, LL; Yang, L |
Article |
GENOME BIOLOGY |
2022 |
| Knowledge graph-based thought: a knowledge graph-enhanced LLM framework for pan-cancer question answering |
Feng, YC; Zhou, L; Ma, C; Zheng, YK; He, RK; Li, YX |
|
GIGASCIENCE |
2025 |
| KPNA3 Confers Sorafenib Resistance to Advanced Hepatocellular Carcinoma via TWIST Regulated Epithelial-Mesenchymal Transition |
Hu, B; Cheng, JW; Hu, JW; Li, H; Ma, XL; Tang, WG; Sun, YF; Guo, W; Huang, A; Zhou, KQ; Gao, PT; Cao, Y; Qiu, SJ; Zhou, J; Fan, J; Yang, XR |
Article |
JOURNAL OF CANCER |
2019 |
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