1. English
  2. 中国科学院
  3. 邮箱登录
  4. ARP平台
 首页 > 人才队伍 > 全体研究组长

全体研究组长

Stefan Gruenewald
博士 研究员 博士生导师

中科院计算生物学重点实验室，系统发生组合数学课题组

研究方向：Phylogenetic Combinatorics

电子邮件(E-mail)：stefan@picb.ac.cn

电话(Tel)：021-54920459

简历
2006.09-present: Principal Investigator, CAS-MPG Partner institute for Computational Biology, CAS, Shanghai, China
2005.09-2006.08: Combined Postdoc, Linnaeus Center for Bioinformatics, Uppsala University in Uppsala, Sweden, and the University of Canterbury in Christchurch, New Zealand.
2001.04-2003.03: Postdoc, Graduate College “Bioinformatics” and Department of Mathematics, University of Bielefeld, Bielefeld, Germany.
1998.04-2001.02: Department of Mathematics, University of Bielefeld, Ph.D. in Mathematics
1994.02-1998.03: Department of Mathematics, University of Bielefeld, Diploma in Mathematics
1991.10-1994.01: Department of Mathematics, University of Bielefeld, Vordiplom (B.Sc. equivalent) in Mathematics

研究内容
1. Developing methods to reconstruct phylogenetic networks
2. Combinatorics and graph theory
3. Applications of phylogenetic methods within and outside phylogenetics

代表性论文（* 通讯作者）

  1. Gong W, Wan L, Lu W, Ma L, Cheng F, Cheng W, Grünewald S, Feng J*. Statistical testing and power analysis for brain-wide association study. Med Image Anal 2018 Jul;47:15-30
  2. Grünewald S, Long Y*, Wu Y. Reconstructing Unrooted Phylogenetic Trees from Symbolic Ternary Metrics. Bull Math Biol 2018 Jun;80(6):1563-1577
  3. He Z#, Han D#, Efimova O, Guijarro P, Yu Q, Oleksiak A, Jiang S, Anokhin K, Velichkovsky B, Grünewald S, Khaitovich P*. Comprehensive transcriptome analysis of neocortical layers in humans, chimpanzees and macaques. Nat Neurosci 2017 Jun;20(6):886-895
  4. Steffen Wolf, Stefan Grünewald*. Sequence, structure and ligand binding evolution of rhodopsin-like G protein-coupled receptors: a crystal structure-based phylogenetic analysis. PLoS One 2015 Apr 16;10(4):e0123533
  5. Jialiang Yang, Stefan Gruenewald, Yifei Xu, Xiufeng Wan*. Quartet-based methods to reconstruct phylogenetic networks. BMC Syst Biol 2014 Feb 20;8:21
  6. Jialiang Yang, Jun Li, Stefan Gruenewald*, Xiufeng Wan*. BinAligner: a heuristic method to align biological networks. BMC Bioinformatics 2013;14(Suppl 14):S8
  7. Jialiang Yang, Stefan Gruenewald, Xiufeng Wan*. Quartet-net: a quartet-based method to reconstruct phylogenetic networks. Mol Biol Evol 2013 May;30(5):1206-1217
  8. Grünewald S*, Spillner A, Bastkowski S, B？gershausen A, Moulton V. SuperQ: computing supernetworks from quartets. IEEE/ACM Trans Comput Biol Bioinform 2013 Jan-Feb;10(1):151-160
  9. Li J, Roebuck P, Grünewald S, Liang H*. SurvNet: a web server for identifying network-based biomarkers that most correlate with patient survival data. Nucleic Acids Res 2012 Jul;40(Web Server issue):W123-W126
  10. Grünewald S, Koolen J, Moulton V, Wu T*. The size of 3-compatible, weakly compatible split systems. J Appl Math Comput 2012 Oct;40(1-2):249-259
  11. Grünewald S*. Slim sets of binary trees. J Comb Theory A 2012 Feb;119(2):323-330
  12. Yang J, Li J, Dong L, Grünewald S. A heuristic algorithm to align protein interaction networks. J Biomath 2011;26(3):569-575
  13. Ding Y, Grünewald S, Humphries J. On agreement forests. J Comb Theory A 2011;118(7):2059-2065
  14. Yang J, Li J, Dong L, Grünewald S. Analysis on the reconstruction accuracy of the Fitch method for inferring ancestral states. BMC Bioinformatics 2011 Jan 13;12:18