1. English
  2. 中国科学院
  3. 邮箱登录
  4. ARP平台
 首页 > 人才队伍 > 全体研究组长

全体研究组长

林旭
博士 研究员 博士生导师

中科院营养代谢与食品安全重点实验室，人类营养与疾病研究组组长

研究方向：营养流行病学

电子邮件(E-mail)：xlin@sibs.ac.cn

电话(Tel)：021-54920249

简历
2017-至     今：中国科学院上海营养与健康所  研究员
2003-2016年：中国科学院上海生科院营养科学研究所 研究员
2008-2015年：中国科学院营养与代谢重点实验室，主任
2008-2014年：中国科学院上海生科院营养科学研究所，所长助理
1999-2003年：美国国立卫生研究院/美国国家老龄研究院，美国杜克大学医学中心老龄研究中心外科系，博士后
1997-1999年：美国国立卫生研究院/美国国家环境卫生科学研究院，北卡罗来那大学医学院病理和实验医学系，博士后
1990-1997年：美国康奈尔大学营养科学分部，营养科学博士

研究内容
1. 遗传和营养生活方式等环境因素，以及基因-环境，基因-表型的相互作用对中国人群肥胖、代谢综合征和2型糖尿病等发病的影响；
2. 组学为基础的生物标记对营养状况和代谢性疾病风险的预测；
3. 代谢性疾病高危人群的膳食营养干预；
4. 遗传和非遗传因素对个体营养需求的影响。

代表性论文（* 通讯作者）

  1. Sun L, Zong G, Li H, Lin X*. Fatty acids and cardiometabolic health: a review of studies in Chinese populations. Eur J Clin Nutr 2021 Feb;75(2):253-266
  2. Shaofeng Huo, Liang Sun, Geng Zong, Boyu Song, He Zheng, Qianlu Jin, Huaixing Li, Xu Lin*. Genetic susceptibility, dietary cholesterol intake and plasma cholesterol levels in a Chinese population. J Lipid Res 2020 Nov;61(11):1504-1511
  3. Yiwei Ma, Liang Sun, Jun Li, Yao Hu, Zhenji Gan, Geng Zong, He Zheng, Qianlu Jin, Huaixing Li, Frank B Hu, Rong Zeng, Qi Sun*, Xu Lin*. Erythrocyte PUFAs, circulating acylcarnitines, and metabolic syndrome risk: a prospective study in Chinese. J Lipid Res 2019 Feb;60(2):421-429
  4. Wang F, Sun L, Sun Q, Liang L, Gao X, Li R, Pan A, Li H, Deng Y, Hu FB, Wu J, Zeng R*, Lin X*. Associations of Plasma Amino Acid and Acylcarnitine Profiles with Incident Reduced Glomerular Filtration Rate. Clin J Am Soc Nephrol 2018 Apr 6;13(4):560-568
  5. Zhu J, Manichaikul A, Hu Y, Chen YI, Liang S, Steffen LM, Rich SS, Tsai M, Siscovick DS, Lemaitre RN, Li H, Lin X*. Meta-analysis of genome-wide association studies identifies three novel loci for saturated fatty acids in East Asians. Eur J Nutr 2017 Jun;56(4):1477-1484
  6. Hu Y, Tanaka T, Zhu J, Guan W, Wu JHY, Psaty BM, McKnight B, King IB, Sun Q, Richard M, Manichaikul A, Frazier-Wood AC, Kabagambe EK, Hopkins PN, Ordovas JM, Ferrucci L, Bandinelli S, Arnett DK, Chen YI, Liang S, Siscovick DS, Tsai MY, Rich SS, Fornage M, Hu FB, Rimm EB, Jensen MK, Lemaitre RN, Mozaffarian D, Steffen LM, Morris AP, Li H, Lin X. Discovery and fine-mapping of loci associated with MUFAs through trans-ethnic meta-analysis in Chinese and European populations. J Lipid Res 2017 May;58(5):974-981
  7. Yao P, Sun L, Lu L, Ding H, Chen X, Tang L, Xu X, Liu G, Hu Y, Ma Y, Wang F, Jin Q, Zheng H, Yin H, Zeng R, Chen Y, Hu FB, Li H*, Lin X*. Effects of Genetic and Non-genetic Factors on Total and Bioavailable 25(OH)D Responses to Vitamin D Supplementation. J Clin Endocrinol Metab 2017 Jan 1;102(1):100-110
  8. Lu X#, Li J#, Li H#, Chen Y, Wang L, He M, Wang Y, Sun L, Hu Y, Huang J, Wang F, Liu X, Chen S, Yu K, Yang X, Mo Z, Lin X*, Wu T*, Gu D*. Coding-sequence variants are associated with blood lipid levels in 14,473 Chinese. Hum Mol Genet 2016 Sep 15;25(18):4107-4116
  9. Sun L, Liang L, Gao X, Zhang H, Yao P, Hu Y, Ma Y, Wang F, Jin Q, Li H, Li R, Liu Y, Hu FB, Zeng R*, Lin X*, Wu J*. Early Prediction of Developing Type 2 Diabetes by Plasma Acylcarnitines: A Population-Based Study. Diabetes Care 2016 Sep;39(9):1563-1570
  10. Liu G, Deng Y, Sun L, Ye X, Yao P, Hu Y, Wang F, Ma Y, Li H, Liu Y, Sun Q*, Lin X*. Elevated plasma tumor necrosis factor-α receptor 2 and resistin are associated with increased incidence of kidney function decline in Chinese adults. Endocrine 2016 Jun;52(3):541-549
  11. Hu Y#, Li H#, Lu L#, Manichaikul A, Zhu J, Chen YD, Sun L, Liang S, Siscovick DS, Steffen LM, Tsai MY, Rich SS, Lemaitre RN, Lin X*. Genome-wide meta-analyses identify novel loci associated with n-3 and n-6 polyunsaturated fatty acid levels in Chinese and European-ancestry populations. Hum Mol Genet 2016 Mar 15;25(6):1215-1224
  12. Yao P, Lu L, Hu Y, Liu G, Chen X, Sun L, Ye X, Zheng H, Chen Y, Hu FB, Li H, Lin X*. A dose-response study of vitamin D3 supplementation in healthy Chinese: a 5-arm randomized, placebo-controlled trial. Eur J Nutr 2016 Feb;55(1):383-392
  13. Ye K, Cao C, Lin X, O'Brien KO*, Gu Z*. Natural selection on HFE in Asian populations contributes to enhanced non-heme iron absorption. BMC Genet 2015 Jun 10;16:61
  14. Ma RC*, Lin X*, Jia W*. Causes of type 2 diabetes in China. Lancet Diabetes Endocrinol 2014 Dec;2(12):980-991
  15. Zong G, Sun Q, Yu D, Zhu J, Sun L, Ye X, Li H, Jin Q, Zheng H, Hu FB, Lin X*. Dairy consumption, type 2 diabetes, and changes in cardiometabolic traits: a prospective cohort study of middle-aged and older Chinese in Beijing and Shanghai. Diabetes Care 2014 Jan;37(1):56-63
  16. Li H, Gan W, Lu L, Dong X, Han X, Hu C, Yang Z, Sun L, Bao W, Li P, He M, Sun L, Wang Y, Zhu J, Ning Q, Tang Y, Zhang R, Wen J, Wang D, Zhu X, Guo K, Zuo X, Guo X, Yang H, Zhou X, DIAGRAM Consortium, AGEN-T2D Consortium, Zhang X, Qi L, Loos RJ, Hu FB, Wu T, Liu Y, Liu L, Yang Z, Hu R, Jia W, Ji L*, Li Y*, Lin X*. A Genome-Wide Association Study Identifies GRK5 and RASGRP1 as Type 2 Diabetes Loci in Chinese Hans. Diabetes 2013 Jan;62(1):291-298
  17. Zong G, Zhu J, Sun L, Ye X, Lu L, Jin Q, Zheng H, Yu Z, Zhu Z, Li H, Sun Q*, Lin X*. Associations of fatty acids in the de novo lipogenesis pathway with risk of metabolic syndrome in middle-aged and older Chinese. Am J Clin Nutr 2013;98(2):319-326